You are not concerned about what is important, but instead are executing a brave man on account of personal enmity!" Li Yuan was impressed by his words, and Li Yuan's son Li Shimin interceded on Li Jing's behalf. At the execution, Li Jing yelled, "You, duke, rose in order to eliminate tyrannical rule for the people. Knowing that Li Jing was planning to report his plans to Emperor Yang, Li Yuan set to execute him. In 617, Li Yuan indeed rebelled, and soon captured Chang'an, declaring Emperor Yang's grandson Yang You the Prince of Dai emperor (as Emperor Gong) but seizing power as regent. However, he was first delivered to Chang'an, and then, as nearly the entire Sui state was engulfed in agrarian rebellions at that time, there was no way to deliver him to Jiangdu from there. Li Jing came to suspect that Li Yuan was plotting a rebellion, and therefore pretended to commit a crime and asked to be locked up and delivered to Emperor Yang, who was then at Jiangdu (江都, in modern Yangzhou, Jiangsu). Near the end of the reign of Emperor Yang, Li Jing served as the vice prefect of the Mayi Commandery (馬邑, roughly modern Shuozhou, Shanxi), when he served under the general Li Yuan the Duke of Tang, who was in charge of the nearby important city of Taiyuan (太原, in modern Taiyuan, Shanxi) against Eastern Tujue forces. He later served as a low level official within the imperial administration, and it was said that he impressed both the prime minister Yang Su and the important minister Niu Hong (牛弘). His maternal uncle was the Sui general Han Qinhu (韓擒虎), and it was said that Han was impressed by his talent, stating, "You are the only person that I can talk to about Sun Tzu's and Wu Qi's strategies."Įarly in his career, Li Jing served as a minor county official for Chang'an county – one of the two counties within Chang'an, which served as Sui's capital. In his youth, Li Jing was said to be handsome and ambitious, and was talented both in literary and military matters. His grandfather Li Chongyi (李崇義) served as a provincial governor during the Northern Wei, and his father, Li Quan (李詮), served as a commandery governor during Sui. Li Jing was born in 571, during the Sui dynasty's predecessor state Northern Zhou. Li Jing and Li Shiji are considered the two most prominent early Tang generals. In 630, Li Jing defeated the Göktürks, led by Jieli Khan, with just 3,000 cavalry soldiers in a surprise attack, allowing the Tang Empire to subjugate the Göktürks and reduce them to the status of a vassal under the Tang Empire. Conclusion:In the binary powder mixtures of TCM, the linearity relationship between density and mass ratio is largely depended on particle size difference of components.Li Jing (571 – July 2, 649 ), courtesy name Yaoshi, posthumously known as Duke Jingwu of Wei (also spelled as Duke of Wey), was a Chinese military general, strategist, and writer who lived in the early Tang dynasty and was most active during the reign of Emperor Taizong. Based on the partial least squares (PLS) model, the variable importance in the projection (VIP) analysis further proved that the mixing mass ratio (VIP value=1.62), α (VIP value=1.13) and D10 (the corresponding particle size when the particle size distribution accumulated to 10%, VIP value=1.06) were the key factors affecting the density of binary powder mixtures of TCM. The α of Stellariae Radix-MCC PH200 binary mixture system was between αc and αr, its density was affected by both of replacement mechanism and filling mechanism. The α of Oroxyli Semen-MCC PH102 binary mixture system was smaller than the critical ratio (αc=0.154 0), and its density was nonlinear with the mass ratio of components, which conformed to the filling mechanism. Result:The α of Angelicae Sinensis Radix-MCC KG802 binary mixture system was larger than the replacement rate (αr=0.741 0), and its density had a good linear relationship with the mass ratio, which conformed to the replacement mechanism. Based on the packing theory and multivariate analysis, the effects of particle size related parameters on the filling structure and density of the binary powder mixtures were elucidated. The particle size distribution, density and other parameters of six single materials and 27 binary powder mixtures were characterized. Binary powder mixtures with nine mass ratios (90∶10, 80∶20, 70∶30, 60∶40, 50∶50, 40∶60, 30∶70, 20∶80 and 10∶90) were prepared for each group, and 27 binary powder mixtures containing TCM were obtained. Method:Three groups of binary powder mixtures with different particle size ratio (α) were constructed, namely Oroxyli Semen-microcrystalline cellulose PH102 (MCC PH102) (α=0.071 7), Stellariae Radix-MCC PH200 (α=0.158 7) and Angelicae Sinensis Radix-MCC KG802 (α=0.840 6). ABSTRACT Objective:To investigate the influence of particle size on density of binary powder mixture of traditional Chinese medicine (TCM), and to provide reference for formulation design of TCM preparations.
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